Infectious Diseases

Research

RESEARCH OUTPUT 2012-2013:
  1. Luetkemeyer AF, Rosenkranz SL, Lu D, Marzan F, Ive P, Hogg E, Swindells S, Benson CA, Grinsztejn B, Sanne IM, Havlir DV, Aweeka F; Adult AIDS Clinical, Trials Group A5221 Study Team. Relationship Between Weight, Efavirenz Exposure, and Virologic Suppression in HIV-Infected Patients on Rifampin-Based Tuberculosis Treatment in the AIDS Clinical Trials Group A5221 STRIDE Study. Clin Infect Dis. 2013 Aug;57(4):586-93. doi: 10.1093/cid/cit246. Epub 2013 Apr 16. PubMed PMID: 23592830; PubMed Central PMCID: PMC3719885.
  2. Kreusch A, Karstaedt AS. Candidemia among adults in Soweto, South Africa, 1990-2007. Int J Infect Dis. 2013 Aug;17(8):e621-3. doi: 10.1016/j.ijid.2013.02.010. Epub 2013 Mar 25. PubMed PMID: 23535300.
  3. Fogel JM, Wang L, Parsons TL, Ou SS, Piwowar-Manning E, Chen Y, Mudhune VO, Hosseinipour MC, Kumwenda J, Hakim JG, Chariyalertsak S, Panchia R, Sanne I, Kumarasamy N, Grinsztejn B, Makhema J, Pilotto J, Santos BR, Mayer KH, McCauley M, Gamble T, Bumpus NN, Hendrix CW, Cohen MS, Eshleman SH. Undisclosed antiretroviral drug use in a multi-national clinical trial (HPTN 052). J Infect Dis. 2013 Aug 1. [Epub ahead of print] PubMed PMID: 23908493.
  4. Nkosi D, Janssen S, Padanilam X, Louw R, Menezes CN, Grobusch MP. Factors influencing specialist care referral of multidrug- and extensively drug-resistant tuberculosis patients in Gauteng/South Africa: a descriptive questionnaire-based study. BMC Health Serv Res. 2013 Jul 9;13:268. doi: 10.1186/1472-6963-13-268. PubMed PMID: 23837531; PubMed Central PMCID: PMC3708743.
  5. Cubasch H, Joffe M, Hanisch R, Schuz J, Neugut AI, Karstaedt A, Broeze N, van den Berg E, McCormack V, Jacobson JS. Breast cancer characteristics and HIV among 1,092 women in Soweto, South Africa. Breast Cancer Res Treat. 2013 Jul;140(1):177-86. doi: 10.1007/s10549-013-2606-y. Epub 2013 Jun 26. PubMed PMID: 23801159; PubMed Central PMCID: PMC3706733.
  6. Venter F, Allais L, Richter M. Exposure Ethics: Does Hiv Pre-Exposure Prophylaxis Raise Ethical Problems for the Health Care Provider and Policy Maker? Bioethics. 2013 Jun 24. doi: 10.1111/bioe.12021. [Epub ahead of print] PubMed PMID: 23796241.
  7. Wahlers K, Menezes CN, Romig T, Kern P, Grobusch MP. Cystic echinococcosis in South Africa: The worst yet to come? Acta Trop. 2013 Jun 14. doi:pii: S0001-706X(13)00149-6. 10.1016/j.actatropica.2013.06.002. [Epub ahead of print] PubMed PMID: 23774317.
  8. Hanrahan CF, Selibas K, Deery CB, Dansey H, Clouse K, Bassett J, Scott L, Stevens W, Sanne I, Van Rie A. Time to treatment and patient outcomes among TB suspects screened by a single point-of-care xpert MTB/RIF at a primary care clinic in Johannesburg, South Africa. PLoS One. 2013 Jun 6;8(6):e65421. doi: 10.1371/journal.pone.0065421. Print 2013. PubMed PMID: 23762367; PubMed Central PMCID: PMC3675091.
  9. Evans D, Menezes C, Mahomed K, Macdonald P, Untiedt S, Levin L, Jaffray I, Bhana N, Firnhaber C, Maskew M. Treatment outcomes of HIV-infected adolescents attending public-sector HIV clinics across Gauteng and Mpumalanga, South Africa. AIDS Res Hum Retroviruses. 2013 Jun;29(6):892-900. doi: 10.1089/AID.2012.0215. Epub 2013 Feb 25. PubMed PMID: 23373540; PubMed Central PMCID: PMC3653371.
  10. Zinn RJ, Serrurier C, Takuva S, Sanne I, Menezes CN. HIV-associated lipodystrophy in South Africa: the impact on the patient and the impact on the plastic surgeon. J Plast Reconstr Aesthet Surg. 2013 Jun;66(6):839-44. doi: 10.1016/j.bjps.2013.02.032. Epub 2013 Mar 30. PubMed PMID: 23545227.
  11. Van Rie A, Page-Shipp L, Mellet K, Scott L, Mkhwnazi M, Jong E, Omar T, Beylis N, Stevens W, Sanne I, Menezes CN. Diagnostic accuracy and effectiveness of the Xpert MTB/RIF assay for the diagnosis of HIV-associated lymph node tuberculosis. Eur J Clin Microbiol Infect Dis. 2013 May 10. [Epub ahead of print] PubMed PMID: 23660698.
  12. Brennan AT, Maskew M, Sanne I, Fox MP. The interplay between CD4 cell count, viral load suppression and duration of antiretroviral therapy on mortality in a resource-limited setting. Trop Med Int Health. 2013 May;18(5):619-31. doi: 10.1111/tmi.12079. Epub 2013 Feb 18. PubMed PMID: 23419157; PubMed Central PMCID: PMC3625450.
  13. Mogoye BK, Menezes CN, Wong ML, Stacey S, von Delft D, Wahlers K, Wassermann M, Romig T, Kern P, Grobusch MP, Frean J. First insights into species and genotypes of Echinococcus in South Africa. Vet Parasitol. 2013 Apr 10. doi:pii: S0304-4017(13)00218-5. 10.1016/j.vetpar.2013.03.033. [Epub ahead of print] PubMed PMID: 23623184.
  14. Menezes CN, Duarte R, Dickens C, Dix-Peek T, Van Amsterdam D, John MA, Ive P, Maskew M, Macphail P, Fox MP, Raal F, Sanne I, Crowther NJ. The early effects of stavudine compared with tenofovir on adipocyte gene expression, mitochondrial DNA copy number and metabolic parameters in South African HIV-infected patients: a randomized trial. HIV Med. 2013 Apr;14(4):217-25. doi: 10.1111/j.1468-1293.2012.01054.x. Epub 2012 Oct 4. PubMed PMID: 23036096.
  15. Fox MP, Maskew M, MacPhail AP, Long L, Brennan AT, Westreich D, MacLeod WB, Majuba P, Sanne IM. Cohort profile: the Themba Lethu Clinical Cohort, Johannesburg, South Africa. Int J Epidemiol. 2013 Apr;42(2):430-9. doi: 10.1093/ije/dys029. Epub 2012 Mar 20. PubMed PMID: 22434860; PubMed Central PMCID: PMC3619949.
  16. Clouse K, Pettifor A, Shearer K, Maskew M, Bassett J, Larson B, Van Rie A, Sanne I, Fox MP. Loss to follow-up before and after delivery among women testing HIV positive during pregnancy in Johannesburg, South Africa. Trop Med Int Health. 2013 Apr;18(4):451-60. doi: 10.1111/tmi.12072. Epub 2013 Feb 3. PubMed PMID: 23374278; PubMed Central PMCID: PMC3600093.
  17. Van Rie A, Page-Shipp L, Hanrahan CF, Schnippel K, Dansey H, Bassett J, Clouse K, Scott L, Stevens W, Sanne I. Point-of-care Xpert® MTB/RIF for smear-negative tuberculosis suspects at a primary care clinic in South Africa. Int J Tuberc Lung Dis. 2013 Mar;17(3):368-72. doi: 10.5588/ijtld.12.0392. PubMed PMID: 23407225.
  18. Clouse K, Pettifor A, Maskew M, Bassett J, Van Rie A, Gay C, Behets F, Sanne I, Fox MP. Initiating antiretroviral therapy when presenting with higher CD4 cell counts results in reduced loss to follow-up in a resource-limited setting. AIDS. 2013 Feb 20;27(4):645-50. doi: 10.1097/QAD.0b013e32835c12f9. PubMed PMID: 23169326; PubMed Central PMCID: PMC3646627.
  19. Phillips E, Bartlett JA, Sanne I, Lederman MM, Hinkle J, Rousseau F, Dunn D, Pavlos R, James I, Mallal SA, Haas DW. Associations between HLA-DRB1*0102, HLA-B*5801, and hepatotoxicity during initiation of nevirapine-containing regimens in South Africa. J Acquir Immune Defic Syndr. 2013 Feb 1;62(2):e55-7. doi: 10.1097/QAI.0b013e31827ca50f. PubMed PMID: 23328091; PubMed Central PMCID: PMC3551216.
  20. Clouse K, Pettifor AE, Maskew M, Bassett J, Van Rie A, Behets F, Gay C, Sanne I, Fox MP. Patient retention from HIV diagnosis through one year on antiretroviral therapy at a primary health care clinic in Johannesburg, South Africa. J Acquir Immune Defic Syndr. 2013 Feb 1;62(2):e39-46. doi: 10.1097/QAI.0b013e318273ac48. PubMed PMID: 23011400; PubMed Central PMCID: PMC3548953.
  21. Schnippel K, Meyer-Rath G, Long L, Stevens WS, Sanne I, Rosen S. Diagnosing Xpert MTB/RIF negative TB: impact and cost of alternative algorithms for South Africa. S Afr Med J. 2013 Jan 14;103(2):101-6. doi: 10.7196/samj.6182. PubMed PMID: 23374320.
  22. Westreich D, Maskew M, Evans D, Firnhaber C, Majuba P, Sanne I. Incident pregnancy and time to death or AIDS among HIV-positive women receiving antiretroviral therapy. PLoS One. 2013;8(3):e58117. doi: 10.1371/journal.pone.0058117. Epub 2013 Mar 8. PubMed PMID: 23520489; PubMed Central PMCID: PMC3592862.
  23. Voss De Lima Y, Evans D, Page-Shipp L, Barnard A, Sanne I, Menezes CN, Van Rie A. Linkage to care and treatment for TB and HIV among people newly diagnosed with TB or HIV-associated TB at a large, inner city South African hospital. PLoS One. 2013;8(1):e49140. doi: 10.1371/journal.pone.0049140. Epub 2013 Jan 16. PubMed PMID: 23341869; PubMed Central PMCID: PMC3547004.
  24. Schnippel K, Rosen S, Shearer K, Martinson N, Long L, Sanne I, Variava E. Costs of inpatient treatment for multi-drug-resistant tuberculosis in South Africa. Trop Med Int Health. 2013 Jan;18(1):109-16. doi: 10.1111/tmi.12018. Epub 2012 Nov 21. PubMed PMID: 23170876.
  25. Maskew M, Westreich D, Firnhaber C, Sanne I. Tenofovir use and pregnancy among women initiating HAART. AIDS. 2012 Nov 28;26(18):2393-7. doi: 10.1097/QAD.0b013e328359a95c. Erratum in: AIDS. 2013 Mar 13;27(5):855. PubMed PMID: 22951630; PubMed Central PMCID: PMC3725726.
  26. Meiring ST, Quan VC, Cohen C, Dawood H, Karstaedt AS, McCarthy KM, Whitelaw AC, Govender NP; Group for Enteric, Respiratory and Meningeal disease Surveillance in South Africa (GERMS-SA). A comparison of cases of paediatric-onset and adult-onset cryptococcosis detected through population-based surveillance, 2005-2007. AIDS. 2012 Nov 28;26(18):2307-14. doi: 10.1097/QAD.0b013e3283570567. PubMed PMID: 22739390.
  27. Wahlers K, Menezes CN, Wong ML, Zeyhle E, Ahmed ME, Ocaido M, Stijnis C, Romig T, Kern P, Grobusch MP. Cystic echinococcosis in sub-Saharan Africa. Lancet Infect Dis. 2012 Nov;12(11):871-80. doi: 10.1016/S1473-3099(12)70155-X. Review. PubMed PMID: 23099081.
  28. Patel M, Philip V, Fazel F, Lakha A, Vorog A, Ali N, Karstaedt A, Pather S. Human immunodeficiency virus infection and chronic myeloid leukemia. Leuk Res. 2012 Nov;36(11):1334-8. doi: 10.1016/j.leukres.2012.07.012. Epub 2012 Aug 4. PubMed PMID: 22867899.
  29. Takuva S, Westreich D, Menezes CN, McNamara L, Sanne I, Page-Shipp L, Maskew M. Antiretroviral therapy initiation during tuberculosis treatment and HIV-RNA and CD4 T-lymphocyte responses. Int J Tuberc Lung Dis. 2012 Oct;16(10):1358-64. doi: 10.5588/ijtld.11.0769. Epub 2012 Aug 3. PubMed PMID: 22863288; PubMed Central PMCID: PMC3727657.
  30. Fox MP, Shearer K, Maskew M, Macleod W, Majuba P, Macphail P, Sanne I. Treatment outcomes after 7 years of public-sector HIV treatment. AIDS. 2012 Sep 10;26(14):1823-8. PubMed PMID: 22739391; PubMed Central PMCID: PMC3600649.
  31. Clouse K, Page-Shipp L, Dansey H, Moatlhodi B, Scott L, Bassett J, Stevens W, Sanne I, Van Rie A. Implementation of Xpert MTB/RIF for routine point-of-care diagnosis of tuberculosis at the primary care level. S Afr Med J. 2012 Sep 7;102(10):805-7. doi: 10.7196/samj.5851. PubMed PMID: 23034211.
  32. Robertson K, Jiang H, Kumwenda J, Supparatpinyo K, Evans S, Campbell TB, Price R, Tripathy S, Kumarasamy N, La Rosa A, Santos B; 5199 study team, Silva MT, Montano S, Kanyama C, Faesen S, Murphy R, Hall C, Marra CM, Marcus C, Berzins, B, Allen R, Housseinipour M, Amod F, Sanne I, Hakim J, Walawander A, Nair A; AIDS Clinical Trials Group. Improved neuropsychological and neurological functioning across three antiretroviral regimens in diverse resource-limited settings: AIDS Clinical Trials Group study a5199, the International Neurological Study. Clin Infect Dis. 2012 Sep;55(6):868-76. Epub 2012 Jun 1. PubMed PMID: 22661489; PubMed Central PMCID: PMC3491853.
  33. Brehm JH, Koontz DL, Wallis CL, Shutt KA, Sanne I, Wood R, McIntyre JA, Stevens WS, Sluis-Cremer N, Mellors JW; CIPRA-SA Project 1 Study Team. Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis. 2012 Sep;55(5):737-45. Epub 2012 May 22. PubMed PMID: 22618567;PubMed Central PMCID: PMC3491849.
  34. Schnippel K, Meyer-Rath G, Long L, MacLeod W, Sanne I, Stevens WS, Rosen S.Scaling up Xpert MTB/RIF technology: the costs of laboratory- vs. clinic-based roll-out in South Africa. Trop Med Int Health. 2012 Sep;17(9):1142-51. doi: 10.1111/j.1365-3156.2012.03028.x. Epub 2012 Jun 12. PubMed PMID: 22686606; PubMed Central PMCID: PMC3506730.
  35. El-Sadr WM, Holmes CB, Mugyenyi P, Thirumurthy H, Ellerbrock T, Ferris R, Sanne I, Asiimwe A, Hirnschall G, Nkambule RN, Stabinski L, Affrunti M, Teasdale C, Zulu I, Whiteside A. Scale-up of HIV treatment through PEPFAR: a historic public health achievement. J Acquir Immune Defic Syndr. 2012 Aug 15;60 Suppl 3:S96-104. doi: 10.1097/QAI.0b013e31825eb27b. Review. PubMed PMID: 22797746; PubMed Central PMCID: PMC3445041.
  36. Azzoni L, Foulkes AS, Firnhaber C, Yin X, Xiang ZQ, Li Y, Stevens W, Gross R, Ertl HC, Sanne I, Montaner LJ. Antiretroviral therapy interruptions result in loss of protective humoral immunity to neoantigens in HIV-infected individuals. AIDS. 2012 Jul 17;26(11):1355-62. doi: 10.1097/QAD.0b013e328354648e. PubMed PMID: 22516873; PubMed Central PMCID: PMC3548620.
  37. Karstaedt AS. Profile of cause of death assigned to adults on antiretroviral therapy in Soweto. S Afr Med J. 2012 Jun 28;102(8):680-2. PubMed PMID: 22831946.
  38. Trataris AN, Arntzen L, Rossouw J, Frean J, Karstaedt A. Bartonella henselae and Bartonella quintana seroprevalence in HIV-positive, HIV-negative and clinically healthy volunteers in Gauteng, South Africa. Onderstepoort J Vet Res. 2012 Jun 20;79(2):E1. doi: 10.4102/ojvr.v79i2.479. PubMed PMID: 23327402.
  39. Mogoye B, Menezes CN, Grobusch MP, Wahlers K, Frean J. Human cystic echinococcosis in South Africa. Onderstepoort J Vet Res. 2012 Jun 20;79(2):E1. doi: 10.4102/ojvr.v79i2.469. PubMed PMID: 23327392.
  40. Trataris AN, Rossouw J, Arntzen L, Karstaedt A, Frean J. Bartonella spp. In human and animal populations in Gauteng, South Africa, from 2007 to 2009. Onderstepoort J Vet Res. 2012 Jun 20;79(2):E1-8. doi: 10.4102/ojvr.v79i2.452. PubMed PMID: 23327372.
  41. Hamers RL, Sigaloff KC, Wensing AM, Wallis CL, Kityo C, Siwale M, Mandaliya K, Ive P, Botes ME, Wellington M, Osibogun A, Stevens WS, Rinke de Wit TF, Schuurman R; PharmAccess African Studies to Evaluate Resistance (PASER). Patterns of HIV-1 drug resistance after first-line antiretroviral therapy (ART) failure in 6 sub-Saharan African countries: implications for second-line ART strategies. Clin Infect Dis. 2012 Jun;54(11):1660-9. doi: 10.1093/cid/cis254. Epub 2012 Apr 3. PubMed PMID: 22474222.
  42. Maskew M, Westreich D, Fox MP, Maotoe T, Sanne IM. Effectiveness and safety of 30 mg versus 40 mg stavudine regimens: a cohort study among HIV-infected adults initiating HAART in South Africa. J Int AIDS Soc. 2012 Mar 12;15(1):13. doi: 10.1186/1758-2652-15-13. PubMed PMID: 22410312; PubMed Central PMCID: PMC3313885.
  43. Kuritzkes DR, Hakim JG, Sanne I. Least among equals. Clin Infect Dis. 2012 Mar;54(6):876-7. doi: 10.1093/cid/cir1048. PubMed PMID: 22357810; PubMed Central PMCID: PMC3284211.
  44. Albrich WC, Madhi SA, Adrian PV, van Niekerk N, Mareletsi T, Cutland C, Wong M, Khoosal M, Karstaedt A, Zhao P, Deatly A, Sidhu M, Jansen KU, Klugman KP. Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia. Clin Infect Dis. 2012 Mar 1;54(5):601-9. doi: 10.1093/cid/cir859. Epub 2011 Dec 8. PubMed PMID: 22156852; PubMed Central PMCID: PMC3275757.
  45. Mitchell M, Hedt BL, Eshun-Wilson I, Fraser H, John MA, Menezes C, Grobusch MP, Jackson J, Taljaard J, Lesh N. Electronic decision protocols for ART patient triaging to expand access to HIV treatment in South Africa: a cross sectional study for development and validation. Int J Med Inform. 2012 Mar;81(3):166-72. doi: 10.1016/j.ijmedinf.2011.11.003. Epub 2011 Dec 16. PubMed PMID: 22178295; PubMed Central PMCID: PMC3279573.
  46. Evans D, Maskew M, Sanne I. Increased risk of mortality and loss to follow-up among HIV-positive patients with oropharyngeal candidiasis and malnutrition before antiretroviral therapy initiation: a retrospective analysis from a large urban cohort in Johannesburg, South Africa. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Mar;113(3):362-72. doi: 10.1016/j.oooo.2011.09.004. PubMed PMID: 22669142; PubMed Central PMCID: PMC3370659.
  47. Venter F, Rees H, Pillay Y, Simelela N, Mbengashe TM, Geffen N, Conradie F, Shisana O, Rech D, Serenata C, Taljaard D, Gray G. The medical proof doesn't get much better than VMMC. S Afr Med J. 2012 Feb 23;102(3 Pt 1):124-5; discussion 125-6. PubMed PMID: 22380896.
  48. Schwartz SR, Mehta SH, Taha TE, Rees HV, Venter F, Black V. High pregnancy intentions and missed opportunities for patient-provider communication about fertility in a South African cohort of HIV-positive women on antiretroviral therapy. AIDS Behav. 2012 Jan;16(1):69-78. doi: 10.1007/s10461-011-9981-3. PubMed PMID: 21656145.
  49. Arenas-Pinto A, Weller I, Ekong R, Grant A, Karstaedt A, Reiss P, Telisinghe L, Weber R, Bolhaar M, Bradman N, Ingram C. Common inherited mitochondrial DNA mutations and nucleoside reverse transcriptase inhibitor-induced severe hyperlactataemia in HIV-infected adults: an exploratory study. Antivir Ther. 2012;17(2):275-82. doi: 10.3851/IMP1947. Epub 2011 Nov 7. Erratum in: Antivir Ther. 2012;17(6):1103-4. PubMed PMID: 22293466.
  50. Wallis CL, Papathanasopolous MA, Fox M, Conradie F, Ive P, Orrell C, Zeinecker J, Sanne I, Wood R, McIntyre J, Stevens W; CIPRA-SA project 1 study team. Low rates of nucleoside reverse transcriptase inhibitor resistance in a well-monitored cohort in South Africa on antiretroviral therapy. Antivir Ther. 2012;17(2):313-20. doi: 10.3851/IMP1985. Epub 2011 Nov 18. PubMed PMID: 22293461; PubMed Central PMCID: PMC3600633.
  51. Campbell TB, Smeaton LM, Kumarasamy N, Flanigan T, Klingman KL, Firnhaber C, Grinsztejn B, Hosseinipour MC, Kumwenda J, Lalloo U, Riviere C, Sanchez J, Melo M, Supparatpinyo K, Tripathy S, Martinez AI, Nair A, Walawander A, Moran L, Chen Y, Snowden W, Rooney JF, Uy J, Schooley RT, De Gruttola V, Hakim JG; PEARLS study team of the ACTG. Efficacy and safety of three antiretroviral regimens for initial treatment of HIV-1: a randomized clinical trial in diverse multinational settings. PLoS Med. 2012;9(8):e1001290. Epub 2012 Aug 14. PubMed PMID: 22936892; PubMed Central PMCID: PMC3419182.
  52. Azzoni L, Foulkes AS, Liu Y, Li X, Johnson M, Smith C, Kamarulzaman AB, Montaner J, Mounzer K, Saag M, Cahn P, Cesar C, Krolewiecki A, Sanne I, Montaner LJ. Prioritizing CD4 count monitoring in response to ART in resource-constrained settings: a retrospective application of prediction-based classification. PLoS Med. 012;9(4):e1001207. doi: 10.1371/journal.pmed.1001207. Epub 2012 Apr 17. PubMed PMID: 22529752; PubMed Central PMCID: PMC3328436.
  53. Meyer-Rath G, Schnippel K, Long L, MacLeod W, Sanne I, Stevens W, Pillay S, Pillay Y, Rosen S. The impact and cost of scaling up GeneXpert MTB/RIF in South Africa. PLoS One. 2012;7(5):e36966. doi: 0.1371/journal.pone.0036966. Epub 2012 May 31. PubMed PMID: 22693561; PubMed Central PMCID: PMC3365041.
  54. Davies NE, Karstaedt AS. Antiretroviral outcomes in South African prisoners: a retrospective cohort analysis. PLoS One. 2012;7(3):e33309. doi:10.1371/journal.pone.0033309. Epub 2012 Mar 21. PubMed PMID: 22470448; PubMed Central PMCID: PMC3310000.
  55. Dhana AV, Howell P, Sanne I, Spencer D. Identification of Mycobacterium tuberculosis from pericardial fluid using the new Xpert M.TB/RIF assay. BMJ Case Reports 2013. Doi:10.1136/bcr-2013-200615